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Beer 中心转抄来的关于丈夫DQ alpha 201的资料
0 S4 f/ _2 [7 m0 k* C+ D/ y"A. DQ Alpha" h. U" l6 ^: B4 b
This test measures whether the DNA of the couple is too closely matched. These tests give you
* {! Z4 f# }% g \ fback two numbers for both members of the couple. In a normal pregnancy the father's DNA in9 G- H( }; x9 Y! u
the baby tells the mother's body to set up a protective reaction around the developing embryo. If
_ v7 m e9 v4 \6 L: athe father's DNA is too closely matched to the mother's, there is a good chance that the embryo
! t1 t5 E3 f1 ocreated by them is unable to differentiate itself from the mother's body. The mother's body then6 p% s) x( g+ K/ I# h0 H
rejects the embryo because it cannot identify the embryo as a baby./ a4 p) l6 T! f
There are two different tests for the DQ, the Alpha and the Beta test. Most patients are only
5 `# B' R: E- d( ?. `+ x* Gtested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3,! ^! L1 m) z/ F, b8 N
1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).! P1 \* Y: @! v
Although there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are% i! _* @% f$ m$ k4 s
significant, so they break those down to one more decimal. If both the mother-to-be's and the* u b# {3 o L1 {) @; a) N; i I
father-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes. @9 D# _. }% B
back with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ5 {, ], h% n+ _1 ?3 ] {( e( w
molecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce% h* A$ H: J9 g
a placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or
6 C# ]) o1 c m t Iclosely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother; i' N! I' q9 q, Q# F& W' n& W
and pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility
) r2 M. C0 H% \7 Fbetween mother and baby was far more common in women successfully delivering babies.
9 @0 T. \# \9 g7 c4 ADQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it5 l" o( J3 `% S/ {/ M# a) K2 t
is also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his% d7 i. b/ M1 V) z, u8 D
numbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of
6 J% P; v8 t- xhis numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his/ K1 H4 J: g3 x9 {: |# ~
embryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to. U4 ~5 W) V2 K' r" V% D1 w$ U
put back more embryos to see if you can produce an embryo that is not DQ 201. If he has both
+ @3 j' q! v1 T% h( jnumbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become2 q, ^0 `& }4 x# Q% I
blighted ova." |
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