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Beer 中心转抄来的关于丈夫DQ alpha 201的资料
, `6 j9 G2 |1 B7 |" H3 S( j% Y"A. DQ Alpha
9 _# x9 E( b+ Z8 A% G* uThis test measures whether the DNA of the couple is too closely matched. These tests give you
K1 i4 W5 c6 H2 Rback two numbers for both members of the couple. In a normal pregnancy the father's DNA in7 l) e! D5 U* a0 U
the baby tells the mother's body to set up a protective reaction around the developing embryo. If! F0 A. x7 A* ^
the father's DNA is too closely matched to the mother's, there is a good chance that the embryo
9 B% D1 |# R& F/ B7 j7 v% m8 Zcreated by them is unable to differentiate itself from the mother's body. The mother's body then5 b6 Z6 e* x, S. p# ?3 {1 q3 h0 K
rejects the embryo because it cannot identify the embryo as a baby.
: n! N: x- ?. \# FThere are two different tests for the DQ, the Alpha and the Beta test. Most patients are only- A1 G* H# w* \* S+ K& g) F9 Z* s
tested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3,
- q& x' Y* Z. H" k1 I Z Z) {1 W# x1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).. I3 q. p" L ~; ~# q
Although there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are2 H' H1 b! \: S8 [% [
significant, so they break those down to one more decimal. If both the mother-to-be's and the
$ @# s# G, i: Q7 m$ i8 X! X" |* Ifather-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
3 E7 o. R9 k+ b N6 aback with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ
. |! E" K3 I8 o- xmolecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce
r m$ t( W2 w' F4 @3 n" ca placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or3 m$ q. w& G" Z" n
closely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother; k, J. D7 k1 E) K3 x
and pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility8 g% R5 |) b) Y2 ]8 n
between mother and baby was far more common in women successfully delivering babies.
8 i3 m6 `4 S" o' g0 N9 @& PDQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it1 v0 ^* b9 r$ {5 t( o6 W
is also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his- U$ }2 f N* i b* L+ H
numbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of8 `1 N: H+ `' ~0 M4 w* C) `
his numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his: ]: x; Q# f- k! n
embryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to
2 t$ J' N* z$ Jput back more embryos to see if you can produce an embryo that is not DQ 201. If he has both
7 ~% K" {6 t' N* e3 u, t7 \numbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become
, Q# Z1 j; I/ `. Q2 pblighted ova." |
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