|
|
Beer 中心转抄来的关于丈夫DQ alpha 201的资料+ T$ R- H/ ~+ s% I) K9 Z
"A. DQ Alpha" \8 [0 |" N. t1 R. O2 i1 l
This test measures whether the DNA of the couple is too closely matched. These tests give you) b1 M$ x; m- p: m( Y0 s& ~$ [
back two numbers for both members of the couple. In a normal pregnancy the father's DNA in3 r) g6 V% e; P: ~1 C
the baby tells the mother's body to set up a protective reaction around the developing embryo. If9 p! L1 b/ m: r4 q# D- D* ?
the father's DNA is too closely matched to the mother's, there is a good chance that the embryo+ g8 k- C! r5 _) S! z1 t
created by them is unable to differentiate itself from the mother's body. The mother's body then0 Y4 \- T/ w8 Q' m1 G Y" j2 e
rejects the embryo because it cannot identify the embryo as a baby.
0 I x3 B8 W! e! F/ K: ]% ?# CThere are two different tests for the DQ, the Alpha and the Beta test. Most patients are only# P, }7 f& P5 Z5 Y% P: ?$ ?; f0 q1 {* D
tested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3,
5 P0 l2 _8 S, P. c2 N' I# \1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).
* x' R# V- D. Y+ w, |$ cAlthough there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are0 M" Z1 \. B9 ^
significant, so they break those down to one more decimal. If both the mother-to-be's and the
! S+ i6 @9 A5 [8 u! Hfather-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
* u6 l/ E7 g7 s( zback with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ' t; C0 `8 d1 ~ p' V0 j: O
molecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce
7 Q/ }# A1 J% w5 Q: b5 F/ [1 u1 wa placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or
+ Q4 | ^# A, }7 y) bclosely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother2 L* u! U- C4 j' o# v2 p9 W
and pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility( p; f* a9 D8 W3 l. G
between mother and baby was far more common in women successfully delivering babies.* ]: c/ B: k9 _- P
DQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it
# Q0 n" s$ }5 G+ \% ]7 mis also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his
: M& y6 G' O6 ?# ^0 snumbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of
: B: o9 ~* F, z, @9 U6 lhis numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his+ v! v% v- j2 Y, @, ^8 A) M; D) a
embryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to
2 h2 T8 z7 i* @* Fput back more embryos to see if you can produce an embryo that is not DQ 201. If he has both
2 g; j. s" \' L' N/ g" D4 v p: Tnumbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become
% T f" a7 ?; r! R# @7 Pblighted ova." |
|
[/url]
发表于 2011-5-14 18:07:00
楼主
