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Beer 中心转抄来的关于丈夫DQ alpha 201的资料
- z8 f4 J4 r& Y7 }& ?' ?2 U"A. DQ Alpha% t3 P3 E* z% a' j% E1 P% W8 w
This test measures whether the DNA of the couple is too closely matched. These tests give you; D+ I1 K$ ?) ~9 Y2 ?
back two numbers for both members of the couple. In a normal pregnancy the father's DNA in
! x$ x! f+ x; K4 jthe baby tells the mother's body to set up a protective reaction around the developing embryo. If
2 _( a N" `1 qthe father's DNA is too closely matched to the mother's, there is a good chance that the embryo a- C: S- l ?( A
created by them is unable to differentiate itself from the mother's body. The mother's body then
6 ~ f/ ?% u4 ?( Y2 P* brejects the embryo because it cannot identify the embryo as a baby.4 b! R) {5 `/ O; Q( t
There are two different tests for the DQ, the Alpha and the Beta test. Most patients are only) x/ u2 D! \+ f1 x
tested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3,
4 b* d, `7 g8 L1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents)." |' i4 b) n% i! A4 [5 W; m
Although there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are
3 w* |- M% e, {& f" S$ u! L7 Ysignificant, so they break those down to one more decimal. If both the mother-to-be's and the
1 l I* T% o% Y& Ffather-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
% N) E5 G9 f% Hback with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ& J4 R: x+ S7 h$ I
molecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce/ E" ]9 m( v: b3 k! c% I/ Y- e
a placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or
; s. i; A. X1 k. P! F oclosely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother
9 }1 I5 |. P% E+ A7 g/ Yand pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility& L/ z9 S- o. {3 ? b
between mother and baby was far more common in women successfully delivering babies.
+ r# A/ n9 p4 JDQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it
7 J6 t( k- _0 m- O+ G; f) g! j8 Wis also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his
, h7 |) B. \: o, j& n# `4 \numbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of
) u/ N& X6 s$ F5 J4 khis numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his: T% [5 t2 X1 B% l( }& c$ r
embryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to
x" A5 _- Z! L( L( |; {* Rput back more embryos to see if you can produce an embryo that is not DQ 201. If he has both! D5 a) P1 \( R: v( B" y# u
numbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become. B+ l" j" C: Y+ S
blighted ova." |
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发表于 2011-5-14 18:07:00
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