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Beer 中心转抄来的关于丈夫DQ alpha 201的资料
5 E4 o5 p8 a% X- p0 c/ f) `"A. DQ Alpha5 ^4 H P! o! y
This test measures whether the DNA of the couple is too closely matched. These tests give you8 {$ z+ R8 W& i: H/ y, {5 Z4 j/ X
back two numbers for both members of the couple. In a normal pregnancy the father's DNA in' d) M2 x: N1 A. u
the baby tells the mother's body to set up a protective reaction around the developing embryo. If
. u3 E# B2 H7 n' _3 I4 O7 rthe father's DNA is too closely matched to the mother's, there is a good chance that the embryo
0 k# H' {) F X" j5 qcreated by them is unable to differentiate itself from the mother's body. The mother's body then
- F& `3 Y6 r' K( Q: T: ]& ?7 Grejects the embryo because it cannot identify the embryo as a baby., x& `; S1 k0 ^& f# k6 X9 ~
There are two different tests for the DQ, the Alpha and the Beta test. Most patients are only
4 E0 B% A% w6 v) C7 m2 v0 ?' otested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3,/ ?- }) V j2 s4 d* i H, f% ^3 n
1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).
9 e- K& o& N% |Although there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are
7 A$ r' \# Z# A: o/ f7 ~significant, so they break those down to one more decimal. If both the mother-to-be's and the
: n/ r" p( h! S) Tfather-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
1 {9 P; u9 H2 P. @! d. Wback with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ# O' p8 l! X; }
molecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce
! f; k2 C5 K/ S: W, S+ Y/ o6 C9 da placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or$ O, q1 ~) z6 h) D$ `1 h; _
closely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother& k/ Q) W. z0 b5 P
and pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility
u& N6 m( L8 X& e, O/ H- fbetween mother and baby was far more common in women successfully delivering babies.( ?% _1 {5 n/ n' _2 V: i! x- f+ I
DQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it+ W5 b2 P. k7 Q/ } [
is also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his! s, [0 a! [& o0 _1 C d, n6 b
numbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of
2 ]/ U& u n$ B" b9 [his numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his
/ X& F J# K; w9 tembryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to3 e1 E, L' L7 v+ o( Q: Y: F
put back more embryos to see if you can produce an embryo that is not DQ 201. If he has both
9 ~* [# v$ @2 m( r) e3 C b0 Gnumbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become) ?! G6 \7 Y2 Z$ @1 a6 D, ^0 `. S
blighted ova." |
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发表于 2011-5-12 23:59:52
