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Beer 中心转抄来的关于丈夫DQ alpha 201的资料
) [9 t0 v2 @. q' J9 N+ }2 ]: R"A. DQ Alpha+ }. J7 J, ~# S
This test measures whether the DNA of the couple is too closely matched. These tests give you
9 |6 y! ~) h4 b5 R) y/ Nback two numbers for both members of the couple. In a normal pregnancy the father's DNA in& p$ f# D0 R6 X9 D
the baby tells the mother's body to set up a protective reaction around the developing embryo. If/ W& t9 z+ O. A: R0 z5 A- m3 o
the father's DNA is too closely matched to the mother's, there is a good chance that the embryo
+ ^- p9 {; m( `9 s9 _created by them is unable to differentiate itself from the mother's body. The mother's body then
" x n; t! t2 x* ]2 F/ [rejects the embryo because it cannot identify the embryo as a baby.; K2 ]7 a! Y* @" C2 ]
There are two different tests for the DQ, the Alpha and the Beta test. Most patients are only" U" T+ I. r& v7 \: N, z0 n0 n% ?
tested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3," r, f4 W% [" s+ L) `" I( `
1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).9 ` p+ \: e3 ^& w4 M- z
Although there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are
: @ C8 y ^4 |) Ksignificant, so they break those down to one more decimal. If both the mother-to-be's and the
+ M3 E R) D9 y+ W" B* afather-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
5 Q& |$ D5 A" Wback with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ! v% h2 H& j7 G2 I" h
molecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce
: B* B2 i0 G0 v8 y+ \' ]1 a ka placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or
: }! ~6 p6 [( a t m' Gclosely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother
* t2 J& j( q; f Aand pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility, y1 z+ F2 U y6 H
between mother and baby was far more common in women successfully delivering babies.
/ d& q) z% h9 C/ X) [' ^DQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it
+ k6 f8 u$ s/ {5 Tis also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his
# ~) A/ s S4 |- Znumbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of
0 E* \6 x9 p( Mhis numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his
( S8 U, d6 d! lembryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to
0 B" G8 O4 D2 d+ zput back more embryos to see if you can produce an embryo that is not DQ 201. If he has both
3 U* P) j6 Q- w5 l' H6 Cnumbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become
1 [7 z/ W% }( u9 g, B: V; z# C+ X. N4 pblighted ova." |
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发表于 2011-5-14 18:07:00
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